article Open AccessTop 10% cited
Intestinal polyposis in mice with a dominant stable mutation of the beta -catenin gene
The EMBO Journal · 1999 · Vol. 18(21) · pp. 5931–5942
Naomoto Harada✉(Merck (Japan))
Wnt/β-catenin signaling in development and cancerCancer-related gene regulationGenetic factors in colorectal cancerBiologyBeta-cateninMutationGeneCancer researchGeneticsBETA (programming language)CateninMolecular biologyWnt signaling pathway
MeSH terms
AnimalsColonic NeoplasmsCytoskeletal ProteinsDisease Models, AnimalGenes, DominantIntestinal NeoplasmsIntestinal PolypsMutationProto-Oncogene ProteinsRecombination, GeneticStem CellsViral ProteinsSignal TransductionTrans-ActivatorsMice, Knockout
Funding
- Ministry of Education, Culture, Sports, Science and Technology
- University of Tokyo
Citations
1,212
FWCI
7.98
field-weighted impact
References
53
Percentile
98%
vs. same field & year
Citations per year
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References
Wnt signaling: a common theme in animal development
Genes & Development · 1997 · 2,571 citations
From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion
Trends in Genetics · 1993 · 985 citations
Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β
Current Biology · 1998 · 844 citations
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs
Nucleic Acids Research · 1987 · 5,158 citations
β-catenin is a target for the ubiquitin–proteasome pathway
The EMBO Journal · 1997 · 2,503 citations
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