review Open AccessTop 1% cited
Functions of RANKL/RANK/OPG in bone modeling and remodeling
Archives of Biochemistry and Biophysics · 2008 · Vol. 473(2) · pp. 139–146
Brendan F. Boyce✉(University of Rochester Medical Center)Lianping Xing(University of Rochester Medical Center)
Bone Metabolism and DiseasesBone health and treatmentsBone health and osteoporosis researchRANKLOsteoprotegerinBone remodelingOsteoclastBone resorptionRANK LigandChemistryActivator (genetics)Stromal cellBone remodeling period
MeSH terms
AnimalsBone ResorptionCell DifferentiationHumansOsteoclastsOsteogenesisSignal TransductionBone RemodelingMiceOsteoprotegerinRANK LigandReceptor Activator of Nuclear Factor-kappa B
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References
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Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts
Developmental Cell · 2002 · 2,657 citations
RANK is essential for osteoclast and lymph node development
Genes & Development · 1999 · 1,484 citations
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Developmental Cell · 2002 · 1,599 citations
Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation
Cell · 1998 · 5,439 citations
A Single-Dose Placebo-Controlled Study of AMG 162, a Fully Human Monoclonal Antibody to RANKL, in Postmenopausal Women
Journal of Bone and Mineral Research · 2004 · 762 citations
Genetic regulation of osteoclast development and function
Nature Reviews Genetics · 2003 · 1,700 citations
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