articleTop 1% cited
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells
Nature Immunology · 2007 · Vol. 8(9) · pp. 942–949
Eva V. Acosta Rodríguez✉(Institute for Research in Biomedicine)Giorgio NapolitaniAntonio LanzavecchiaFederica Sallusto
Psoriasis: Treatment and PathogenesisT-cell and B-cell ImmunologyIL-33, ST2, and ILC PathwaysInterleukin 17Interleukin 12BiologyPriming (agriculture)Cell biologyImmunologyTransforming growth factorInterleukinAntigen-presenting cellT cell
MeSH terms
Antigen-Presenting CellsCell DifferentiationCells, CulturedEnzyme-Linked Immunosorbent AssayFlow CytometryT-Lymphocytes, Helper-InducerHumansReceptors, Thyroid HormoneInterleukin-6T-Lymphocyte SubsetsCytokinesTransforming Growth Factor betaReceptors, Retinoic AcidInterleukin-12Cell Lineage
Funding
- National Institute for Health and Care Research
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Bundesamt für Gesundheit
- National Institutes of Health
Citations
1,798
FWCI
60.31
field-weighted impact
References
43
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100%
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References
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Nature Immunology · 2005 · 4,203 citations
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
Arthritis & Rheumatism · 1999 · 939 citations
Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
Nature Immunology · 2005 · 4,662 citations
TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells
Immunity · 2006 · 3,566 citations
Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation
The Journal of Experimental Medicine · 2003 · 1,633 citations
Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells
Nature Immunology · 2007 · 1,799 citations
Increased expression of interleukin 17 in inflammatory bowel disease
Gut · 2002 · 1,688 citations
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.
The Journal of Experimental Medicine · 1994 · 5,139 citations
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