articleTop 10% cited
Four-Hydroxynonenal, a Product of Lipid Peroxidation, is Increased in the Brain in Alzheimer’s Disease
Neurobiology of Aging · 1998 · Vol. 19(1) · pp. 33–36
William R. Markesbery✉(University of Kentucky)Mark A. Lovell(University of Kentucky)
Alzheimer's disease research and treatmentsBiochemical Acid Research StudiesCholinesterase and Neurodegenerative Diseases4-HydroxynonenalLipid peroxidationDiseaseNeuroscienceMedicineChemistryBiochemistryPathologyPsychologyOxidative stress
MeSH terms
AgedAged, 80 and overAldehydesAlzheimer DiseaseAmygdalaBrain ChemistryFemaleHippocampusHumansMaleLipid PeroxidationCysteine Proteinase InhibitorsOxidative Stress
Funding
- National Institutes of Health
Citations
677
FWCI
10.77
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References
42
Percentile
99%
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References
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Journal of Biological Chemistry · 1951 · 317,666 citations
Four-Hydroxynonenal, a Product of Lipid Peroxidation, is Increased in the Brain in Alzheimer’s Disease
Neurobiology of Aging · 1998 · 677 citations
A Role for 4‐Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, in Disruption of Ion Homeostasis and Neuronal Death Induced by Amyloid β‐Peptide
Journal of Neurochemistry · 1997 · 775 citations
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
Annals of Neurology · 1994 · 1,030 citations
Oxidative Stress Hypothesis in Alzheimer's Disease
Free Radical Biology and Medicine · 1997 · 2,368 citations
Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation
Journal of Neurochemistry · 1995 · 776 citations
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
Free Radical Biology and Medicine · 1991 · 6,615 citations
4‐Hydroxynonenal‐Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease
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