reviewTop 1% cited
Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress
Free Radical Biology and Medicine · 2002 · Vol. 32(11) · pp. 1050–1060
D. Allan Butterfield✉(University of Kentucky)Christopher M. Lauderback(University of Kentucky)
Alzheimer's disease research and treatmentsBiochemical effects in animalsCholinesterase and Neurodegenerative DiseasesLipid peroxidationOxidative stressAmyloid (mycology)Amyloid betaOxidative phosphorylationChemistryBiochemistryFree-radical theory of agingPeptideNeuroscience
MeSH terms
Alzheimer DiseaseAnimalsFree RadicalsHumansOxidation-ReductionLipid PeroxidationAmyloid beta-PeptidesOxidative Stress
Funding
- National Institutes of Health
Citations
990
FWCI
19.52
field-weighted impact
References
122
Percentile
100%
vs. same field & year
Citations per year
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References
Biochemistry and pathology of radical-mediated protein oxidation
Biochemical Journal · 1997 · 1,683 citations
Acrolein is increased in Alzheimer’s disease brain and is toxic to primary hippocampal cultures
Neurobiology of Aging · 2001 · 445 citations
Increased Peroxidation and Reduced Antioxidant Enzyme Activity in Alzheimer's Disease
Experimental Neurology · 1998 · 511 citations
Four-Hydroxynonenal, a Product of Lipid Peroxidation, is Increased in the Brain in Alzheimer’s Disease
Neurobiology of Aging · 1998 · 677 citations
A Role for 4‐Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, in Disruption of Ion Homeostasis and Neuronal Death Induced by Amyloid β‐Peptide
Journal of Neurochemistry · 1997 · 775 citations
Oxidation of methionyl residues in proteins: Tools, targets, and reversal
Free Radical Biology and Medicine · 1995 · 876 citations
Oxidative Stress Hypothesis in Alzheimer's Disease
Free Radical Biology and Medicine · 1997 · 2,368 citations
Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation
Journal of Neurochemistry · 1995 · 776 citations
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