articleTop 1% cited
Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure
Biological Psychiatry · 2011 · Vol. 69(8) · pp. 754–761
Nanxin Li✉(Yale University)Rong-Jian Liu(Yale University)Jason M. Dwyer(Yale University)Mounira Banasr(Yale University)Boyoung Lee(Korea Institute of Science and Technology)Hyeon Son(Hanyang University)Xiaoyuan Li(Yale University)George K. Aghajanian(Yale University)Ronald S. Duman(Yale University)
Treatment of Major DepressionTryptophan and brain disordersNeuroscience and Neuropharmacology ResearchNMDA receptorNeuroscienceGlutamate receptorPrefrontal cortexExcitatory postsynaptic potentialLong-term depressionSynaptic plasticityAMPA receptorPharmacologyAntidepressant
MeSH terms
AnimalsBehavior, AnimalChoice BehaviorElectrophysiologyKetamineSynaptic TransmissionNeuronsPhenolsPiperidinesStress, PhysiologicalStress, PsychologicalSynapsesBlotting, WesternSignal TransductionReceptors, N-Methyl-D-Aspartate
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