review Open AccessTop 1% cited
mTOR signaling: At the crossroads of plasticity, memory and disease
Trends in Neurosciences · 2009 · Vol. 33(2) · pp. 67–75
Charles A. Hoeffer✉(New York University)Eric Klann(New York University)
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology ResearchIon channel regulation and functionmTORC2PI3K/AKT/mTOR pathwaymTORC1NeuroscienceSynaptic plasticityTranslation (biology)BiologySignal transductionMechanistic target of rapamycinNeuroplasticity
MeSH terms
AnimalsGene Expression RegulationHumansMemoryModels, BiologicalNervous System DiseasesNeuronal PlasticitySignal TransductionProtein Serine-Threonine KinasesIntracellular Signaling Peptides and ProteinsMiceTOR Serine-Threonine Kinases
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Developmental Cell · 2006 · 1,398 citations
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A complex interplay between Akt, TSC2 and the two mTOR complexes
Biochemical Society Transactions · 2009 · 710 citations
Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton
Current Biology · 2004 · 2,646 citations
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