reviewTop 1% cited
Signaling pathways underlying the rapid antidepressant actions of ketamine
Neuropharmacology · 2011 · Vol. 62(1) · pp. 35–41
Ronald S. Duman✉(Yale University)Nanxin Li(Yale University)Rong-Jian Liu(Yale University)Vanja Đurić(Yale University)George K. Aghajanian(Yale University)
Treatment of Major DepressionTryptophan and brain disordersNeuroscience and Neuropharmacology ResearchSynaptogenesisKetamineAntidepressantNeuroscienceNMDA receptorPrefrontal cortexSynapseHippocampusMilnacipranMedicine
MeSH terms
AnimalsAntidepressive AgentsDepressionGene Expression RegulationHumansKetamineModels, BiologicalNeuronsSynapsesSignal TransductionNeurogenesis
Citations
528
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Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure
Biological Psychiatry · 2011 · 1,074 citations
Experience-dependent structural synaptic plasticity in the mammalian brain
Nature reviews. Neuroscience · 2009 · 1,936 citations
Antidepressant effects of ketamine in depressed patients
Biological Psychiatry · 2000 · 3,787 citations
Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors
Biological Psychiatry · 2007 · 1,097 citations
mTOR signaling: At the crossroads of plasticity, memory and disease
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A Neurotrophic Model for Stress-Related Mood Disorders
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