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Activity and mechanisms of action of selected biocidal agents on Gram-positive and -negative bacteria

Journal of Applied Microbiology · 2003 · Vol. 94(2) · pp. 240–247
Susannah E. WalshJean‐Yves MaillardA.D. RussellCarl E. CatrenichDuane CharbonneauRobert G. Bartolo

Abstract

The ingredients evaluated demonstrated a range of bactericidal and bacteriostatic properties against the Gram-negative and -positive organisms evaluated and the membrane (leakage of intracellular components) was implicated in the mode of action for most (except TCC). Sub-MIC levels of all ingredients did induce subtle effects on the organisms which impacted bacterial growth, even for those which had no true inhibitory effects.

Antimicrobial agents and applicationsEssential Oils and Antimicrobial ActivityPhenothiazines and Benzothiazines Synthesis and ActivitiesThymolEugenolAntimicrobialChemistryMicrobiologyBacteriaMode of actionMinimum bactericidal concentrationMinimum inhibitory concentrationMembrane permeability

MeSH terms

Quaternary Ammonium CompoundsAnti-Bacterial AgentsCarbanilidesEdetic AcidEscherichia coliEugenolMicrobial Sensitivity TestsPotassiumPseudomonas aeruginosaSesquiterpenesStaphylococcus aureusSurface-Active AgentsThymol
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