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R (−)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine

Pharmacology Biochemistry and Behavior · 2013 · Vol. 116 · pp. 137–141
Ji‐chun ZhangSu‐Xia LiKenji Hashimoto
Treatment of Major DepressionTryptophan and brain disordersFunctional Brain Connectivity StudiesKetamineAntidepressantPotencyPharmacologyPsychologyMedicineAnesthesiaPsychiatryChemistry

MeSH terms

AnimalsAntidepressive AgentsKetamineStereoisomerismMice

Funding

  • Ministry of Education, Culture, Sports, Science and Technology
  • Japan Society for the Promotion of Science
Citations
347
FWCI
14.50
field-weighted impact
References
34
Percentile
99%
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Citations per year
Cited by
Mechanisms of ketamine action as an antidepressant
Molecular Psychiatry · 2018 · 1,063 citations
References
Antidepressant effects of ketamine in depressed patients
Biological Psychiatry · 2000 · 3,787 citations
Ketamine
Anesthesia & Analgesia · 1998 · 609 citations
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