Scinovex
Subscribe
R

Randal J. Kaufman

Howard Hughes Medical InstituteORCID https://orcid.org/0000-0003-4277-316X
h-index
—
Publications
—
Citations
—
i10-index
—
Impact (2-yr)
—

Top Publications

THE MAMMALIAN UNFOLDED PROTEIN RESPONSE
Annual Review of Biochemistry20053,009 citations
Mechanisms, regulation and functions of the unfolded protein response
Nature Reviews Molecular Cell Biology20202,455 citations
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls
Genes & Development19992,249 citationsFirst authorCorresponding
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
Nature Cell Biology20131,664 citationsCorresponding
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling
The Journal of Cell Biology20051,467 citations
Translational Control Is Required for the Unfolded Protein Response and In Vivo Glucose Homeostasis
Molecular Cell20011,342 citationsCorresponding
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
Molecular and Cellular Biology20031,204 citations
Endoplasmic reticulum stress in liver disease
Journal of Hepatology20101,163 citations
ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
Cell Death and Differentiation2006912 citations
From acute ER stress to physiological roles of the Unfolded Protein Response
Cell Death and Differentiation2006867 citations
The role of ER stress in lipid metabolism and lipotoxicity
Journal of Lipid Research2016639 citationsCorresponding
Randal J. Kaufman · Scinovex