reviewTop 1% cited
Endoplasmic reticulum stress in liver disease
Journal of Hepatology · 2010 · Vol. 54(4) · pp. 795–809
Harmeet Malhi✉(University of Michigan–Ann Arbor)Randal J. Kaufman(University of Michigan–Ann Arbor)
Endoplasmic Reticulum Stress and DiseaseLiver Disease Diagnosis and TreatmentPancreatic function and diabetesUnfolded protein responseEndoplasmic reticulumXBP1Activating transcription factorATF6Protein kinase RATF4Cell biologyEIF-2 kinaseTranscription factor
MeSH terms
Endoplasmic Reticulum Chaperone BiPAnimalsCholestasisEndoplasmic ReticulumFatty LiverCarcinoma, HepatocellularHumansInflammationLiver DiseasesLiver Diseases, AlcoholicLiver NeoplasmsModels, BiologicalProtein ConformationStress, PhysiologicalReperfusion Injury
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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
Genes & Development · 1998 · 2,003 citations
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