Scinovex
review Open AccessTop 1% cited

Important Flavonoids and Their Role as a Therapeutic Agent

Molecules · 2020 · Vol. 25(22) · pp. 5243–5243
Asad UllahSidra MunirSyed Lal BadshahNoreen KhanLubna GhaniBenjamin Gabriel PoulsonAbdul‐Hamid EmwasMariusz Jaremko

Abstract

Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuroprotective and cardio-protective effects. These biological activities depend upon the type of flavonoid, its (possible) mode of action, and its bioavailability. These cost-effective medicinal components have significant biological activities, and their effectiveness has been proved for a variety of diseases. The most recent work is focused on their isolation, synthesis of their analogs, and their effects on human health using a variety of techniques and animal models. Thousands of flavonoids have been successfully isolated, and this number increases steadily. We have therefore made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.

Flavonoids in Medical ResearchPhytochemicals and Antioxidant ActivitiesBioactive natural compoundsPhytochemicalFlavonoidHuman healthHealth benefitsMode of actionTraditional medicineBioavailabilityBiologyChemistryPharmacology

MeSH terms

Alzheimer DiseaseAnimalsAnti-Inflammatory AgentsAntifungal AgentsAntimalarialsAntineoplastic AgentsAntioxidantsAntiviral AgentsCardiovascular SystemFlavonoidsHumansHypoglycemic AgentsNervous SystemNeuronsPlant Extracts
Citations
1,519
FWCI
84.61
field-weighted impact
References
305
Percentile
100%
vs. same field & year
Citations per year
Cited by
Phytochemical and antioxidant activity of Diospyros kaki Leaves
Journal of Medicinal Plants Studies · 2023 · 3 citations
Antiviral activities of flavonoids
Biomedicine & Pharmacotherapy · 2021 · 384 citations
An updated review on flavonoids
The Pharma Innovation · 2024 · 3 citations
References
Flavonoids: antioxidants or signalling molecules?
Free Radical Biology and Medicine · 2004 · 1,990 citations
Flavonoids: a review of probable mechanisms of action and potential applications
American Journal of Clinical Nutrition · 2001 · 3,041 citations
Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders
European Journal of Medicinal Chemistry · 2017 · 527 citations
Related articles
Exploration of phytochemical potential on flower of Butea monosperma
Journal of Pharmacognosy and Phytochemistry · 2019 · 4 citations
Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.