article Open AccessTop 1% cited

Haplotype-resolved de novo assembly using phased assembly graphs with hifiasm

Nature Methods · 2021 · Vol. 18(2) · pp. 170–175

Haoyu Cheng✉(Harvard University)Gregory T. Concepcion(Pacific Biosciences (United States))Xiaowen Feng(Harvard University)Haowen Zhang(Georgia Institute of Technology)Heng Li(Harvard University)

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Genomics and Phylogenetic Studies Genetic Associations and Epidemiology Genetic Mapping and Diversity in Plants and AnimalsContiguitySequence assemblySequence (biology)GraphHaplotypeFeature (linguistics)

MeSH terms

AlgorithmsHaplotypesGenomeSequence Analysis, DNA

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5,181

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260.31

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BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs

Bioinformatics · 2015 · 14,183 citations

Phased diploid genome assembly with single-molecule real-time sequencing

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Nature Biotechnology · 2019 · 5,994 citations

Minimap2: pairwise alignment for nucleotide sequences

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Canu: scalable and accurate long-read assembly via adaptive <i>k</i> -mer weighting and repeat separation

Genome Research · 2017 · 8,028 citations

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