article Open AccessTop 1% cited
Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19
Nature Medicine · 2020 · Vol. 26(6) · pp. 842–844
Mingfeng Liao(Shenzhen Third People’s Hospital)Yang Liu(Shenzhen Third People’s Hospital)Jing Yuan(Shenzhen Third People’s Hospital)Yanling Wen(Shenzhen Third People’s Hospital)Gang Xu(Shenzhen Third People’s Hospital)Juanjuan Zhao(Shenzhen Third People’s Hospital)Lin Cheng(Shenzhen Third People’s Hospital)Jinxiu Li(Shenzhen Third People’s Hospital)Xin Wang(Shenzhen Third People’s Hospital)Fuxiang Wang(Shenzhen Third People’s Hospital)Lei Liu(Southern University of Science and Technology)Ido Amit✉(Weizmann Institute of Science)Shuye Zhang✉(Shanghai Public Health Clinical Center)Zheng Zhang(Southern University of Science and Technology)
Immune Cell Function and InteractionRespiratory viral infections researchSingle-cell and spatial transcriptomicsBronchoalveolar lavageImmune systemImmunologyProinflammatory cytokineCD8PathogenesisCoronavirus disease 2019 (COVID-19)MedicineInflammationBiology
MeSH terms
BetacoronavirusCOVID-19SARS-CoV-2Bronchoalveolar Lavage FluidHumansPneumonia, ViralCoronavirus InfectionsCD8-Positive T-LymphocytesPandemicsSingle-Cell Analysis
Funding
- National Natural Science Foundation of China
- Science, Technology and Innovation Commission of Shenzhen Municipality
Citations
2,706
FWCI
180.27
field-weighted impact
References
30
Percentile
100%
vs. same field & year
Citations per year
Cited by
SARS-CoV-2 spike protein S1 subunit induces pro-inflammatory responses via toll-like receptor 4 signaling in murine and human macrophages
Heliyon · 2021 · 266 citations
Immunology of COVID-19: Current State of the Science
Immunity · 2020 · 1,775 citations
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Nature Immunology · 2020 · 1,364 citations
Coronavirus biology and replication: implications for SARS-CoV-2
Nature Reviews Microbiology · 2020 · 3,331 citations
References
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Proceedings of the National Academy of Sciences · 2005 · 55,472 citations
STAR: ultrafast universal RNA-seq aligner
Bioinformatics · 2012 · 54,639 citations
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data
Genome biology · 2015 · 3,474 citations
SCENIC: single-cell regulatory network inference and clustering
Nature Methods · 2017 · 6,605 citations
Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites
Cell Reports · 2017 · 1,073 citations
Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis
American Journal of Respiratory and Critical Care Medicine · 2018 · 1,246 citations
Comprehensive Integration of Single-Cell Data
Cell · 2019 · 16,351 citations
Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis
European Respiratory Journal · 2019 · 788 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
