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Structural basis for human coronavirus attachment to sialic acid receptors

Nature Structural & Molecular Biology · 2019 · Vol. 26(6) · pp. 481–489
M. Alejandra TortoriciAlexandra C. WallsYifei LangChunyan WangZeshi LiDanielle KoerhuisGeert‐Jan BoonsBerend‐Jan BoschF.A. ReyRaoul J. de GrootDavid Veesler
SARS-CoV-2 and COVID-19 ResearchViral gastroenteritis research and epidemiologyBacteriophages and microbial interactionsCoronavirusGlycoproteinHemagglutinin (influenza)BiologyLipid bilayer fusionViral entryReceptorViral envelopeSialic acidCell biology

MeSH terms

HumansModels, MolecularReceptors, Cell SurfaceCoronavirus InfectionsN-Acetylneuraminic AcidCryoelectron MicroscopyCoronavirus OC43, HumanVirus InternalizationProtein MultimerizationHEK293 CellsSpike Glycoprotein, Coronavirus

Funding

  • National Science Foundation
  • Burroughs Wellcome Fund
  • Fund for Astrophysical Research
  • University of Washington
  • Nederlandse Organisatie voor Wetenschappelijk Onderzoek
  • China Scholarship Council
  • Centre National de la Recherche Scientifique
  • National Institutes of Health
  • National Institute of General Medical Sciences
  • California NanoSystems Institute
Citations
634
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References
93
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100%
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