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Optimal Determination of Particle Orientation, Absolute Hand, and Contrast Loss in Single-particle Electron Cryomicroscopy

Journal of Molecular Biology · 2003 · Vol. 333(4) · pp. 721–745
Peter B. RosenthalRichard A. Henderson
Advanced Electron Microscopy Techniques and ApplicationsATP Synthase and ATPases ResearchEnzyme Structure and FunctionSingle particle analysisCryo-electron microscopyTilt (camera)Particle (ecology)Orientation (vector space)Contrast transfer functionElectron microscopeOpticsPhysicsChemistry

MeSH terms

AcetyltransferasesGeobacillus stearothermophilusBacterial ProteinsComputer SimulationModels, MolecularProtein ConformationPyruvate Dehydrogenase ComplexCrystallography, X-RayCryoelectron MicroscopyMacromolecular SubstancesDihydrolipoyllysine-Residue Acetyltransferase
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