review Open AccessTop 1% cited
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Nature Genetics · 2018 · Vol. 50(8) · pp. 1112–1121
James J. Lee(University of Minnesota)Robbee Wedow(University of Colorado Boulder)Aysu Okbay✉(Cognitive Research (United States))Edward Kong(Harvard University)Omeed Maghzian(Harvard University)Meghan Zacher(Harvard University)Tuan Anh Nguyen-Viet(University of Southern California)Peter N. Bowers(Harvard University)Julia Sidorenko(The University of Queensland)Richard Karlsson Linnér(Vrije Universiteit Amsterdam)Mark Alan Fontana(University of Southern California)Tushar Kundu(University of Southern California)Chan Wook Lee(Harvard University)Hui Li(Harvard University)Ruoxi Li(University of Southern California)Rebecca Royer(University of Southern California)Pascal Timshel(Statens Serum Institut)Raymond K. Walters(Broad Institute)Emily A. Willoughby(University of Minnesota)Loïc Yengo(The University of Queensland)Maris Alver(University of Tartu)Yanchun Bao(University of Essex)David W. Clark(University of Edinburgh)Felix R. Day(University of Cambridge)Nicholas A. Furlotte(23andMe (United States))Peter K. Joshi(University Hospital of Lausanne)Kathryn E. Kemper(The University of Queensland)Aaron Kleinman(23andMe (United States))Claudia Langenberg(University of Cambridge)Reedik Mägi(University of Tartu)Joey W. Trampush(University of Southern California)Shefali Setia-Verma(Geisinger Health System)Yang Wu(The University of Queensland)Max Lam(Institute of Mental Health)Jing Hua Zhao(University of Cambridge)Zhili Zheng(The University of Queensland)Jason D. Boardman(University of Colorado Boulder)Harry Campbell(University of Edinburgh)Jeremy Freese(Stanford University)Kathleen Mullan Harris(University of North Carolina at Chapel Hill)Caroline Hayward(Institute of Genetics and Cancer)Pamela Herd(University of Essex)Meena Kumari(University of Essex)Todd Lencz(Feinstein Institute for Medical Research)Jian’an Luan(University of Cambridge)Anil K. Malhotra(Feinstein Institute for Medical Research)Andres Metspalu(University of Tartu)Lili Milani(University of Tartu)Ken K. Ong(University of Cambridge)John R. B. Perry(University of Cambridge)David J. Porteous(University of Edinburgh)Marylyn D. Ritchie(Geisinger Health System)Melissa Smart(University of Edinburgh)Blair H. Smith(University of Dundee)Joyce Y. Tung(23andMe (United States))Nicholas J. Wareham(University of Cambridge)James F. Wilson(Institute of Genetics and Cancer)Jonathan Beauchamp(University of Toronto)Dalton Conley(Princeton University)Tōnu Esko(University of Tartu)Steven F. Lehrer(National Bureau of Economic Research)Patrik K. E. Magnusson(Karolinska Institutet)Sven Oskarsson(Uppsala University)Tune H. Pers(Statens Serum Institut)Matthew R. Robinson(The University of Queensland)Kevin Thom(New York University)Chelsea Watson(University of Southern California)Christopher F. Chabris(Autism & Developmental Medicine Institute)Michelle N. Meyer(Geisinger Health System)David Laibson(Harvard University)Jian Yang(The University of Queensland)Magnus Johannesson(Stockholm School of Economics)Philipp Koellinger(Vrije Universiteit Amsterdam)Patrick Turley(Broad Institute)Peter M. Visscher(Queensland University of Technology)Daniel J. Benjamin(University of Southern California)David Cesarini(National Bureau of Economic Research)
Genetic Associations and EpidemiologyGenetics and Neurodevelopmental DisordersGenetic Mapping and Diversity in Plants and AnimalsGenome-wide association studyBiologySingle-nucleotide polymorphismEducational attainmentMultifactorial InheritanceHeritabilityGenetic associationGeneticsSNPGene
MeSH terms
AdultAgedAged, 80 and overEducational StatusFemaleHumansMaleMiddle AgedPhenotypeCohort StudiesMultifactorial InheritancePolymorphism, Single NucleotideGenome-Wide Association Study
Funding
- Open Philanthropy Project
- Karolinska Institutet
- Vetenskapsrådet
- National Institutes of Health
- Medical Research Council
- Biotechnology and Biological Sciences Research Council
- Economic and Social Research Council
- National Institute on Aging
Citations
2,805
FWCI
218.61
field-weighted impact
References
50
Percentile
100%
vs. same field & year
Citations per year
Cited by
A brief history of organoids
American Journal of Physiology-Cell Physiology · 2020 · 516 citations
Benefits and limitations of genome-wide association studies
Nature Reviews Genetics · 2019 · 2,137 citations
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
The Lancet Neurology · 2019 · 2,465 citations
Clinical use of current polygenic risk scores may exacerbate health disparities
Nature Genetics · 2019 · 2,803 citations
Tutorial: a guide to performing polygenic risk score analyses
Nature Protocols · 2020 · 1,959 citations
References
Partitioning heritability by functional annotation using genome-wide association summary statistics
Nature Genetics · 2015 · 2,993 citations
Large-scale gene function analysis with the PANTHER classification system
Nature Protocols · 2013 · 2,572 citations
A Versatile Gene-Based Test for Genome-wide Association Studies
The American Journal of Human Genetics · 2010 · 835 citations
MAGMA: Generalized Gene-Set Analysis of GWAS Data
PLoS Computational Biology · 2015 · 3,882 citations
A global reference for human genetic variation
Nature · 2015 · 19,538 citations
METAL: fast and efficient meta-analysis of genomewide association scans
Bioinformatics · 2010 · 5,672 citations
Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled‐up primate brain
The Journal of Comparative Neurology · 2009 · 2,253 citations
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
Nature Genetics · 2015 · 6,093 citations
Related articles
Pathway analysis of seven common diseases assessed by genome-wide association
Genomics · 2008 · 347 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
