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Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

Nature Genetics · 2015 · Vol. 47(9) · pp. 979–986
Jimmy Z. LiuSuzanne van SommerenHailiang HuangSiew C. NgRudi AlbertsAtsushi TakahashiStephan RipkeJames LeeLuke Jostins-DeanTejas ShahShifteh AbedianJae Hee CheonJudy H. ChoNaser Ebrahim DaryaniLude FrankeYuta FuyunoAilsa HartRamesh C. JuyalGarima JuyalWon Ho KimAndrew P. MorrisHossein PoustchiWilliam G. NewmanVandana MidhaTimothy R. OrchardHomayon VahediAjit SoodJoseph J.�Y. SungReza MalekzadehHarm-Jan WestraKeiko YamazakiSuk-Kyun YangJeffrey C. BarrettAndre FrankeBehrooz Z AlizadehMiles ParkesB.K. ThelmaMark DalyMichiaki KuboCarl A. AndersonRinse K. Weersma
Inflammatory Bowel DiseaseSystemic Lupus Erythematosus ResearchGenetic Associations and EpidemiologyBiologyInflammatory bowel diseaseGenome-wide association studyGenetic associationGeneticsUlcerative colitisGenetic architectureLocus (genetics)DiseaseAllele

MeSH terms

Colitis, UlcerativeCrohn DiseaseGene FrequencyHumansRisk FactorsCase-Control StudiesGenetic Predisposition to DiseasePolymorphism, Single NucleotideGenome-Wide Association StudyGenetic Loci

Funding

  • Eli and Edythe Broad Foundation
  • Wellcome Trust
  • National Institute for Health and Care Research
  • King's College London
  • Nederlandse Organisatie voor Wetenschappelijk Onderzoek
  • Tehran University of Medical Sciences and Health Services
  • Medical Research Council
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References
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