review Open AccessTop 1% cited
AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance
Molecular Cell · 2017 · Vol. 66(6) · pp. 789–800
Daniel Garcia✉(Salk Institute for Biological Studies)Reuben J. Shaw(Salk Institute for Biological Studies)
Metabolism, Diabetes, and CancerPancreatic function and diabetesNatural Antidiabetic Agents StudiesAMPKBiologyRegulatorCell biologyProtein kinase AAMP-activated protein kinasePhosphorylationKinaseNutrient sensingEnergy homeostasis
MeSH terms
AnimalsAutophagyEnergy MetabolismEnzyme ActivationHumansMetabolic DiseasesMitochondriaModels, MolecularPhosphorylationProtein ConformationStructure-Activity RelationshipSignal TransductionEnzyme ActivatorsAMP-Activated Protein KinasesTOR Serine-Threonine Kinases
Funding
- Leona M. and Harry B. Helmsley Charitable Trust
- National Institutes of Health
Citations
1,896
FWCI
51.27
field-weighted impact
References
110
Percentile
100%
vs. same field & year
Citations per year
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References
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Nature Cell Biology · 2011 · 6,906 citations
LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade
Current Biology · 2003 · 1,631 citations
AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
Cell Metabolism · 2011 · 1,713 citations
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
Cell Metabolism · 2005 · 1,557 citations
AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
Molecular Cell · 2008 · 3,735 citations
Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
Cell Metabolism · 2005 · 1,371 citations
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