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A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Cell · 2017 · Vol. 169(7) · pp. 1276–1290.e17
Hadas Keren‐ShaulAmit SpinradAssaf WeinerOrit Matcovitch-NatanRaz Dvir-SzternfeldTyler K. UllandEyal DavidKuti BaruchDavid Lara-AstaisoBeáta TóthShalev ItzkovitzMarco ColonnaMichal SchwartzIdo Amit
Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsImmune cells in cancerTREM2MicrogliaNeurodegenerationBiologyCell typeDownregulation and upregulationImmune systemAlzheimer's diseaseNeuroscienceGenetically modified mouse

MeSH terms

Alzheimer DiseaseAnimalsHumansMice, TransgenicPhagocytesReceptors, ImmunologicSequence Analysis, RNAMicrogliaNeurodegenerative DiseasesMiceSingle-Cell Analysis

Funding

  • Minerva Foundation
  • Ministry of Science, Technology and Space
  • Israel Science Foundation
  • National Institutes of Health
  • European Research Council
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A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease · Scinovex