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Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice

Biological Psychiatry · 2017 · Vol. 82(7) · pp. 472–487
Aurelijus BurokasSilvia ArboleyaRachel D. MoloneyVeronica L. PetersonKiera MurphyGerard ClarkeCatherine StantonTimothy G. DinanJohn F. Cryan
Gut microbiota and healthTryptophan and brain disordersGastrointestinal motility and disordersPrebioticGut floraCorticosteroneAnxiolyticGut–brain axisAntidepressantInternal medicineEndocrinologyMedicinePsychology

MeSH terms

Gastrointestinal MicrobiomeAnimalsAntidepressive AgentsAnxietyBrainCorticosteroneDepressionDisease Models, AnimalLocomotionMaleMice, Inbred C57BLOligosaccharidesStress, PsychologicalAnti-Anxiety AgentsTryptophan

Funding

  • Mead Johnson Nutrition
  • Science Foundation Ireland
  • APC Microbiome Institute
Citations
926
FWCI
37.16
field-weighted impact
References
66
Percentile
100%
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Citations per year
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