articleTop 1% cited
The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
Molecular Psychiatry · 2012 · Vol. 18(6) · pp. 666–673
Gerard Clarke✉(University College Cork)Sue Grenham(University College Cork)Paul Scully(University College Cork)Patrick Fitzgerald(University College Cork)Rachel D. Moloney(University College Cork)Fergus Shanahan(University College Cork)Timothy G. Dinan(University College Cork)John F. Cryan(University College Cork)
Gut microbiota and healthTryptophan and brain disordersNeuroendocrine regulation and behaviorSerotonergicNeurochemicalGut–brain axisBiologyMicrobiomeSerotoninGut floraCentral nervous system5-Hydroxyindoleacetic acidHippocampal formation
MeSH terms
Analysis of VarianceAnimalsBody WeightDisease Models, AnimalFemaleGene Expression RegulationHippocampusHydroxyindoleacetic AcidLipopolysaccharidesMaleReceptors, SerotoninSerotoninSex CharacteristicsStress, PsychologicalTryptophan
Citations
1,838
FWCI
18.26
field-weighted impact
References
67
Percentile
100%
vs. same field & year
Citations per year
Cited by
Regulation of Neurotransmitters by the Gut Microbiota and Effects on Cognition in Neurological Disorders
Nutrients · 2021 · 813 citations
The Impact of Diet and Lifestyle on Gut Microbiota and Human Health
Nutrients · 2014 · 1,516 citations
Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis
Nutrients · 2016 · 865 citations
The role of inflammation and the gut microbiome in depression and anxiety
Journal of Neuroscience Research · 2019 · 478 citations
The Gut-Brain Axis: How Microbiota and Host Inflammasome Influence Brain Physiology and Pathology
Frontiers in Immunology · 2020 · 759 citations
The gut microbiota–brain axis in behaviour and brain disorders
Nature Reviews Microbiology · 2020 · 1,952 citations
Microbiota is essential for social development in the mouse
Molecular Psychiatry · 2013 · 856 citations
Neurotransmitter modulation by the gut microbiota
Brain Research · 2018 · 1,433 citations
References
Establishment of the gut microbiota in Western infants
Acta Paediatrica · 2009 · 655 citations
The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice
Gastroenterology · 2011 · 1,713 citations
A unique central tryptophan hydroxylase isoform
Biochemical Pharmacology · 2003 · 731 citations
Monitoring tryptophan metabolism in chronic immune activation
Clinica Chimica Acta · 2005 · 552 citations
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression
Neuroscience · 2010 · 988 citations
Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice
The Journal of Physiology · 2004 · 2,635 citations
Brain?Gut?Microbe Communication in Health and Disease
Frontiers in Physiology · 2011 · 954 citations
In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice
Molecular Psychiatry · 2004 · 604 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.