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Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers

Psychopharmacology · 2014 · Vol. 232(10) · pp. 1793–1801
Kristin SchmidtPhilip J. CowenCatherine J. HarmerGeorge TzortzisSteven P. ErringtonPhilip W. J. Burnet

Abstract

The suppression of the neuroendocrine stress response and the increase in the processing of positive versus negative attentional vigilance in subjects supplemented with B-GOS are consistent with previous findings of endocrine and anxiolytic effects of microbiota proliferation. Further studies are therefore needed to test the utility of B-GOS supplementation in the treatment of stress-related disorders.

Stress Responses and CortisolTryptophan and brain disordersGut microbiota and healthPlaceboVigilance (psychology)PrebioticAnxietyPsychologyMedicineInternal medicineAnxiolyticEndocrine systemEndocrinology

MeSH terms

AdolescentAdultAnimalsDouble-Blind MethodEmotionsFemaleHumansHydrocortisoneMaleMiddle AgedOligosaccharidesPhotic StimulationSalivaWakefulnessDietary Supplements

Funding

  • Wellcome Trust
  • Medical Research Council
  • Biotechnology and Biological Sciences Research Council
Citations
515
FWCI
9.91
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References
69
Percentile
99%
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References
The Structured Clinical Interview for DSM-III-R (SCID)
Archives of General Psychiatry · 1992 · 4,383 citations
The HPA axis in major depression: classical theories and new developments
Trends in Neurosciences · 2008 · 1,920 citations
The Evolution of the Cognitive Model of Depression and Its Neurobiological Correlates
American Journal of Psychiatry · 2008 · 1,498 citations
How do you feel — now? The anterior insula and human awareness
Nature reviews. Neuroscience · 2008 · 6,534 citations
A cognitive-motivational analysis of anxiety
Behaviour Research and Therapy · 1998 · 1,634 citations
An Inventory for Measuring Depression
Archives of General Psychiatry · 1961 · 37,929 citations
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