article Open AccessTop 1% cited
Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers
Psychopharmacology · 2014 · Vol. 232(10) · pp. 1793–1801
Kristin Schmidt✉(Warneford Hospital)Philip J. Cowen(Warneford Hospital)Catherine J. Harmer(Warneford Hospital)George Tzortzis(Clasado BioSciences (United Kingdom))Steven P. Errington(Newcastle Hospitals - Campus for Ageing and Vitality)Philip W. J. Burnet(University of Oxford)
Abstract
The suppression of the neuroendocrine stress response and the increase in the processing of positive versus negative attentional vigilance in subjects supplemented with B-GOS are consistent with previous findings of endocrine and anxiolytic effects of microbiota proliferation. Further studies are therefore needed to test the utility of B-GOS supplementation in the treatment of stress-related disorders.
Stress Responses and CortisolTryptophan and brain disordersGut microbiota and healthPlaceboVigilance (psychology)PrebioticAnxietyPsychologyMedicineInternal medicineAnxiolyticEndocrine systemEndocrinology
MeSH terms
AdolescentAdultAnimalsDouble-Blind MethodEmotionsFemaleHumansHydrocortisoneMaleMiddle AgedOligosaccharidesPhotic StimulationSalivaWakefulnessDietary Supplements
Funding
- Wellcome Trust
- Medical Research Council
- Biotechnology and Biological Sciences Research Council
Citations
515
FWCI
9.91
field-weighted impact
References
69
Percentile
99%
vs. same field & year
Citations per year
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