articleTop 1% cited
FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase
Cancer Cell · 2016 · Vol. 31(1) · pp. 127–141
Zejuan Li(University of Chicago)Hengyou Weng(University of Cincinnati Medical Center)Rui Su(University of Cincinnati Medical Center)Xiaocheng Weng(Howard Hughes Medical Institute)Zhixiang Zuo(Sun Yat-sen University)Chenying Li(First Affiliated Hospital Zhejiang University)Huilin Huang(University of Chicago)Sigrid Nachtergaele(University of Chicago)Lei Dong(University of Cincinnati Medical Center)Chao Hu(First Affiliated Hospital Zhejiang University)Xi Qin(University of Cincinnati Medical Center)Lichun Tang(Baylor College of Medicine)Yungui Wang(University of Cincinnati Medical Center)Gia-Ming Hong(University of Chicago)Hao Huang(University of Chicago)Xiao Wang(Howard Hughes Medical Institute)Ping Chen(University of Chicago)Sandeep Gurbuxani(University of Chicago)Stephen Arnovitz(University of Chicago)Yuanyuan Li(University of Chicago)Shenglai Li(University of Chicago)Jennifer Strong(University of Cincinnati Medical Center)Mary Beth Neilly(University of Chicago)Richard A. Larson(University of Chicago)Xi Jiang(University of Cincinnati Medical Center)Pumin Zhang(Baylor College of Medicine)Jie Jin(First Affiliated Hospital Zhejiang University)Chuan He✉(University of Chicago)Jianjun Chen✉(University of Cincinnati Medical Center)
RNA modifications and cancerCancer-related gene regulationEpigenetics and DNA MethylationDemethylaseMyeloid leukemiaN6-MethyladenosineBiologyCancer researchRNA methylationMyeloidOncogeneLeukemiaRetinoic acid
MeSH terms
Alpha-Ketoglutarate-Dependent Dioxygenase FTORetinoic Acid Receptor alphaNucleophosminAdenosineHumansMethylationTretinoinLeukemia, Myeloid, AcuteApoptosisCell ProliferationSuppressor of Cytokine Signaling ProteinsTranscriptome
Funding
- American Cancer Society
- Leukemia and Lymphoma Society
- Gabrielle's Angel Foundation for Cancer Research
- China Scholarship Council
- National Institutes of Health
Citations
1,607
FWCI
44.73
field-weighted impact
References
75
Percentile
100%
vs. same field & year
Citations per year
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References
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
Blood · 1988 · 2,413 citations
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
Nature Cell Biology · 2014 · 1,318 citations
Gene expression regulation mediated through reversible m6A RNA methylation
Nature Reviews Genetics · 2014 · 1,978 citations
Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
Cell Reports · 2014 · 1,241 citations
Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits
PLoS Genetics · 2007 · 1,720 citations
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Proceedings of the National Academy of Sciences · 2005 · 55,472 citations
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
Molecular Cell · 2012 · 3,616 citations
Model-based Analysis of ChIP-Seq (MACS)
Genome biology · 2008 · 19,514 citations
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