review Open AccessTop 1% cited
Post-transcriptional gene regulation by mRNA modifications
Nature Reviews Molecular Cell Biology · 2016 · Vol. 18(1) · pp. 31–42
Boxuan Zhao✉(Howard Hughes Medical Institute)Ian A. Roundtree(University of Chicago)Chuan He(University of Chicago)
RNA modifications and cancerRNA Research and SplicingRNA and protein synthesis mechanismsGene expressionCell biologyMessenger RNARegulation of gene expressionGeneTranscriptional regulationComputational biologyBiologyGenetics
MeSH terms
AdenosineAnimalsCell CycleCell DifferentiationCircadian RhythmGene Expression RegulationHumansMethylationNucleic Acid ConformationRNA Processing, Post-TranscriptionalRNA, MessengerProtein BiosynthesisRNA Stability5-Methylcytosine
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References
HuR and mRNA stability
Cellular and Molecular Life Sciences · 2001 · 1,085 citations
m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells
Cell stem cell · 2014 · 1,358 citations
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
Nature Cell Biology · 2014 · 1,318 citations
NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs
Cell Reports · 2013 · 599 citations
Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA
Immunity · 2005 · 2,527 citations
MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
Molecular Cell · 2007 · 3,788 citations
Gene expression regulation mediated through reversible m6A RNA methylation
Nature Reviews Genetics · 2014 · 1,978 citations
Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
Cell Reports · 2014 · 1,241 citations
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