articleTop 1% cited
Evidence That Curcumin Suppresses the Growth of Malignant Gliomas in Vitro and in Vivo through Induction of Autophagy: Role of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways
Molecular Pharmacology · 2007 · Vol. 72(1) · pp. 29–39
Hiroshi Aoki✉Yasunari Takada(The University of Texas MD Anderson Cancer Center)Seiji Kondo(The University of Texas MD Anderson Cancer Center)Raymond SawayaBharat B. AggarwalYasuko Kondo(The University of Texas MD Anderson Cancer Center)
Autophagy in Disease and TherapyCurcumin's Biomedical ApplicationsCalpain Protease Function and RegulationAutophagyCurcuminPI3K/AKT/mTOR pathwayProtein kinase BProgrammed cell deathCell biologySignal transductionBiologyCancer cellApoptosis
MeSH terms
AnimalsAntineoplastic AgentsAutophagyCell DivisionCurcuminGliomaHumansProtein KinasesG2 PhaseNF-kappa BMAP Kinase Signaling SystemRibosomal Protein S6 Kinases, 70-kDaCell Line, TumorExtracellular Signal-Regulated MAP KinasesProto-Oncogene Proteins c-akt
Citations
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75
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Cell · 2000 · 28,385 citations
Curcumin (Diferuloylmethane) Down-Regulates Expression of Cell Proliferation and Antiapoptotic and Metastatic Gene Products through Suppression of IκBα Kinase and Akt Activation
Molecular Pharmacology · 2005 · 528 citations
Phase I Clinical Trial of Oral Curcumin
Clinical Cancer Research · 2004 · 1,233 citations
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