review Open AccessTop 1% cited
YAP/TAZ at the Roots of Cancer
Cancer Cell · 2016 · Vol. 29(6) · pp. 783–803
Francesca Zanconato✉(University of Padua)Michelangelo Cordenonsi(University of Padua)Stefano Piccolo(University of Padua)
Hippo pathway signaling and YAP/TAZHippo signaling pathwayMechanotransductionCancerCancer researchMetastasisCell biologyCancer cellBiologyCell growthTumor microenvironment
MeSH terms
Hippo Signaling PathwayYAP-Signaling ProteinsTranscriptional Coactivator with PDZ-Binding Motif ProteinsAnimalsHumansNeoplasmsPhosphoproteinsTranscription FactorsNeoplastic Stem CellsSignal TransductionTrans-ActivatorsProtein Serine-Threonine KinasesDrug Resistance, NeoplasmMechanotransduction, CellularIntracellular Signaling Peptides and Proteins
Funding
- Ministero dell’Istruzione, dell’Università e della Ricerca
- Associazione Italiana per la Ricerca sul Cancro
- European Research Council
- Horizon 2020
Citations
1,904
FWCI
84.13
field-weighted impact
References
237
Percentile
100%
vs. same field & year
Citations per year
Cited by
Cellular Mechanotransduction: From Tension to Function
Frontiers in Physiology · 2018 · 943 citations
YAP/TAZ upstream signals and downstream responses
Nature Cell Biology · 2018 · 1,083 citations
Ferroptosis: mechanisms, biology and role in disease
Nature Reviews Molecular Cell Biology · 2021 · 6,790 citations
References
The Biology of YAP/TAZ: Hippo Signaling and Beyond
Physiological Reviews · 2014 · 1,805 citations
The Hippo Signaling Pathway in Development and Cancer
Developmental Cell · 2010 · 2,278 citations
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
Nature Cell Biology · 2013 · 1,387 citations
Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups
Acta Neuropathologica · 2011 · 555 citations
The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
Developmental Cell · 2010 · 814 citations
Hippo pathway regulation by cell morphology and stress fibers
Development · 2011 · 848 citations
Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
Nature Cell Biology · 2015 · 1,233 citations
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Genes & Development · 2007 · 3,113 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.