article Open AccessTop 1% cited
The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
Developmental Cell · 2010 · Vol. 19(1) · pp. 27–38
Nailing Zhang✉(Johns Hopkins University)Haibo Bai(Johns Hopkins University)Karen K David(Johns Hopkins University)Jixin Dong(Johns Hopkins University)Yonggang Zheng(Johns Hopkins University)Jing Cai(Johns Hopkins University)Marco Giovannini(House Clinic)Pentao Liu(Wellcome Sanger Institute)Robert A. Anders(Johns Hopkins University)Duojia Pan(Johns Hopkins University)
Hippo pathway signaling and YAP/TAZWnt/β-catenin signaling in development and cancerUbiquitin and proteasome pathwaysMerlin (protein)BiologyHippo signaling pathwayCell biologyEffectorSuppressorTranscription factorKinaseYAP1Carcinogenesis
MeSH terms
YAP-Signaling ProteinsAnimalsBase SequenceBile DuctsCell SurvivalHeterozygoteHomeostasisLiverMice, Inbred C57BLMutationOrgan SizePhenotypePhosphoproteinsSignal TransductionDNA Primers
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References
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Genes & Development · 2007 · 3,113 citations
YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells
Current Biology · 2007 · 1,265 citations
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