reviewTop 1% cited
Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases
Neuropharmacology · 2016 · Vol. 112(Pt B) · pp. 373–388
Michael D. Lovelace(St Vincent's Clinic)Bianca VarneyGayathri SundaramMatthew J. LennonChai K. Lim(Macquarie University)Kelly R. Jacobs(Macquarie University)Gilles J. Guillemin(Macquarie University)Bruce J. Brew✉(St Vincent's Clinic)
Tryptophan and brain disordersBipolar Disorder and TreatmentStress Responses and CortisolQuinolinic acidKynurenic acidKynurenine pathwayKynurenineNeuroprotectionIndoleamine 2,3-dioxygenasePharmacologyBiologyBiochemistryGlutamate receptor
MeSH terms
AnimalsHumansKynurenineNervous System DiseasesTryptophanMetabolic Networks and Pathways
Funding
- University of New South Wales
- LG Display
Citations
376
FWCI
10.35
field-weighted impact
References
193
Percentile
99%
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Citations per year
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References
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Journal of Neurochemistry · 1991 · 759 citations
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
Nature Medicine · 2003 · 2,279 citations
Inhibition of T Cell Proliferation by Macrophage Tryptophan Catabolism
The Journal of Experimental Medicine · 1999 · 1,603 citations
Monitoring tryptophan metabolism in chronic immune activation
Clinica Chimica Acta · 2005 · 552 citations
Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS
European Journal of Pharmacology · 1981 · 751 citations
Huntington's disease: from molecular pathogenesis to clinical treatment
The Lancet Neurology · 2010 · 1,697 citations
The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells
The Journal of Immunology · 2006 · 1,030 citations
Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2007 · 353 citations
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