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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Nature Medicine · 2003 · Vol. 9(10) · pp. 1269–1274
Catherine UyttenhoveLuc PilotteIvan ThéateVincent StroobantDidier ColauNicolas ParmentierThierry BoonBenoı̂t J. Van den Eynde
Tryptophan and brain disordersCancer, Stress, Anesthesia, and Immune ResponseImmune cells in cancerIndoleamine 2,3-dioxygenaseImmune systemTryptophanCancer researchEconomic shortageImmune toleranceImmunologyTryptophan MetabolismBiologyChemistry

MeSH terms

AnimalsFemaleHumansNeoplasm TransplantationNeoplasmsPlacentaPregnancyRNA, MessengerTryptophanTryptophan OxygenaseCD8-Positive T-LymphocytesTumor EscapeCell Line, TumorIndoleamine-Pyrrole 2,3,-DioxygenaseMice
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