articleTop 1% cited
Huntington's disease: from molecular pathogenesis to clinical treatment
The Lancet Neurology · 2010 · Vol. 10(1) · pp. 83–98
Christopher A. Ross✉(Johns Hopkins Medicine)Sarah J. Tabrizi(University College London)
Genetic Neurodegenerative DiseasesMitochondrial Function and PathologyNeurological disorders and treatmentsHuntington's diseaseHuntingtinDiseaseNeurodegenerationHuntingtin ProteinNeuroscienceTrinucleotide repeat expansionMedicinePathogenesisBioinformatics
MeSH terms
Huntingtin ProteinAnimalsBrainDisease Models, AnimalHumansHuntington DiseaseMagnetic Resonance ImagingModels, BiologicalNerve Tissue ProteinsNeuronsNuclear ProteinsPeptidesDisease ProgressionHistory, 20th Century
Funding
- CHDI Foundation
- Research Councils UK
- Medical Research Council
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1,697
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Regional and cellular gene expression changes in human Huntington's disease brain
Human Molecular Genetics · 2006 · 825 citations
Detection of Huntington's disease decades before diagnosis: the Predict-HD study
Journal of Neurology Neurosurgery & Psychiatry · 2007 · 807 citations
Unified Huntington's disease rating scale: Reliability and consistency
Movement Disorders · 1996 · 2,052 citations
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