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ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
Bioinformatics · 2009 · Vol. 25(8) · pp. 1091–1093
Gabriela Bindea(Assistance Publique – Hôpitaux de Paris)Bernhard Mlecnik(Graz University of Technology)Hubert Hackl(Université Paris Cité)Pornpimol Charoentong(Sorbonne Université)Marie Tosolini(Université Paris Cité)Amos Kirilovsky(Graz University of Technology)Wolf H. Fridman(Université Paris Cité)Franck Pagès(Inserm)Zlatko Trajanoski(Sorbonne Université)Jérôme Galon✉(Assistance Publique – Hôpitaux de Paris)
Abstract
We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.
Bioinformatics and Genomic NetworksBiomedical Text Mining and OntologiesGene expression and cancer classificationDECIPHERKEGGPlug-inAnnotationComputer scienceGene ontologyOntologyGene AnnotationRepresentation (politics)Computational biology
MeSH terms
Multigene FamilyModels, BiologicalSoftwareComputational BiologyDatabases, GeneticGene Regulatory Networks
Funding
- Institut National de la Santé et de la Recherche Médicale
- Institut National Du Cancer
Citations
6,609
FWCI
15.60
field-weighted impact
References
11
Percentile
99%
vs. same field & year
Citations per year
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References
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Genome biology · 2007 · 2,525 citations
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Nature Genetics · 2000 · 43,975 citations
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Genome biology · 2003 · 1,209 citations
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
Genome Research · 2003 · 53,132 citations
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