article Open AccessTop 1% cited
The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus
American Journal Of Pathology · 2009 · Vol. 174(4) · pp. 1241–1251
Jeroen J.M. Hoozemans✉(Vrije Universiteit Amsterdam)Elise S. van Haastert(Vrije Universiteit Amsterdam)Diana A.T. Nijholt(Academic Medical Center)Annemieke J.M. Rozemüller(Vrije Universiteit Amsterdam)Piet Eikelenboom(University of Amsterdam)Wiep Scheper(Academic Medical Center)
Endoplasmic Reticulum Stress and DiseaseAlzheimer's disease research and treatmentsNeuroscience and Neuropharmacology ResearchUnfolded protein responseNeurodegenerationEndoplasmic reticulumGSK-3HippocampusPhosphorylationHippocampal formationTau proteinBiologyProtein kinase A
MeSH terms
Sequestosome-1 ProteinGlycogen Synthase Kinase 3 betaAgedAged, 80 and overAlzheimer DiseaseInclusion BodiesEndoribonucleasesFemaleHippocampusHumansImmunohistochemistryMaleMiddle AgedNeuronsPhosphorylation
Funding
- European Commission
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Internationale Stichting Alzheimer Onderzoek
Citations
579
FWCI
11.85
field-weighted impact
References
59
Percentile
99%
vs. same field & year
Citations per year
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References
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The unfolded protein response is activated in Alzheimer’s disease
Acta Neuropathologica · 2005 · 546 citations
Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response
PLoS Biology · 2006 · 997 citations
Neuropathological stageing of Alzheimer-related changes
Acta Neuropathologica · 1991 · 16,076 citations
Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
Neuron · 2007 · 2,239 citations
The glamour and gloom of glycogen synthase kinase-3
Trends in Biochemical Sciences · 2004 · 1,510 citations
Linking of Autophagy to Ubiquitin-Proteasome System Is Important for the Regulation of Endoplasmic Reticulum Stress and Cell Viability
American Journal Of Pathology · 2007 · 709 citations
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