articleTop 10% cited
The unfolded protein response is activated in Alzheimer’s disease
Acta Neuropathologica · 2005 · Vol. 110(2) · pp. 165–172
Jeroen J.M. Hoozemans✉(University of Amsterdam)Robert Veerhuis(Amsterdam UMC Location VUmc)Elise S. van Haastert(Academic Medical Center)Annemieke J.M. Rozemüller(University of Amsterdam)Frank Baas(Academic Medical Center)Piet Eikelenboom(University of Amsterdam)Wiep Scheper(University of Amsterdam)
Endoplasmic Reticulum Stress and DiseaseAlzheimer's disease research and treatmentsAutophagy in Disease and TherapyUnfolded protein responseNeurodegenerationEndoplasmic reticulumNeuroprotectionCell biologyBiologyProtein kinase AWestern blotChaperone (clinical)Kinase
MeSH terms
Endoplasmic Reticulum Chaperone BiPAdultAgedAged, 80 and overAlzheimer DiseaseBrainEndoplasmic ReticulumFemaleHeat-Shock ProteinsHumansMaleMiddle AgedNeuronsBlotting, WesternNeurofibrillary Tangles
Funding
- Internationale Stichting Alzheimer Onderzoek
Citations
546
FWCI
6.79
field-weighted impact
References
22
Percentile
98%
vs. same field & year
Citations per year
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References
The Global Deterioration Scale for assessment of primary degenerative dementia
American Journal of Psychiatry · 1982 · 4,970 citations
The Endoplasmic Reticulum Stress-Responsive Protein GRP78 Protects Neurons Against Excitotoxicity and Apoptosis: Suppression of Oxidative Stress and Stabilization of Calcium Homeostasis
Experimental Neurology · 1999 · 439 citations
Neuropathological stageing of Alzheimer-related changes
Acta Neuropathologica · 1991 · 16,076 citations
Staging of alzheimer's disease-related neurofibrillary changes
Neurobiology of Aging · 1995 · 2,350 citations
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