article Open AccessTop 1% cited
Linking of Autophagy to Ubiquitin-Proteasome System Is Important for the Regulation of Endoplasmic Reticulum Stress and Cell Viability
American Journal Of Pathology · 2007 · Vol. 171(2) · pp. 513–524
Wen-Xing Ding(University of Pittsburgh)Hong-Min Ni(University of Pittsburgh)Wentao Gao(University of Pittsburgh)Tamotsu Yoshimori(National Institute of Genetics)Donna B. Stolz(University of Pittsburgh)David Ron(New York University)Xiao-Ming Yin✉(University of Pittsburgh)
Autophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseAdvanced Glycation End Products researchEndoplasmic reticulumAutophagyProteasomeCell biologyUbiquitinBiologyUbiquitin-Protein LigasesUnfolded protein responseCellApoptosis
MeSH terms
AutophagyCell SurvivalEndoplasmic ReticulumEndoribonucleasesHumansLeupeptinsMembrane ProteinsMicroscopy, ElectronMicrotubule-Associated ProteinsRecombinant Fusion ProteinsTransfectionVacuolesImmunoblottingCysteine Proteinase InhibitorsApoptosis
Funding
- American Liver Foundation
- Harvard University
- Johns Hopkins University
- National Institutes of Health
Citations
709
FWCI
23.52
field-weighted impact
References
54
Percentile
100%
vs. same field & year
Citations per year
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References
ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
Cell Death and Differentiation · 2006 · 912 citations
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
The EMBO Journal · 2000 · 6,511 citations
ERAD: the long road to destruction
Nature Cell Biology · 2005 · 1,198 citations
Coupling endoplasmic reticulum stress to the cell death program
Cell Death and Differentiation · 2004 · 1,197 citations
Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response
PLoS Biology · 2006 · 997 citations
Development by Self-Digestion
Developmental Cell · 2004 · 3,629 citations
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
Nature Genetics · 2004 · 2,306 citations
THE MAMMALIAN UNFOLDED PROTEIN RESPONSE
Annual Review of Biochemistry · 2005 · 3,009 citations
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