articleTop 1% cited
The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults
Free Radical Biology and Medicine · 2003 · Vol. 34(4) · pp. 496–502
Levi Yant(University of Wisconsin–Madison)Qitao Ran(The University of Texas Health Science Center at San Antonio)Lin Rao(University of Wisconsin–Madison)Holly Van Remmen(The University of Texas Health Science Center at San Antonio)Toru Shibatani(The University of Texas Health Science Center at San Antonio)Jason G Belter(University of Wisconsin–Madison)Lucia Motta(University of Wisconsin–Madison)Arlan Richardson(The University of Texas Health Science Center at San Antonio)Tomas A. Prolla✉(University of Wisconsin–Madison)
Selenium in Biological SystemsSex and Gender in HealthcareGPX4Phospholipid-hydroperoxide glutathione peroxidaseLipid peroxidationOxidative stressChemistryAntioxidantCell biologySelenoproteinGlutathione peroxidaseBiochemistry
MeSH terms
Phospholipid Hydroperoxide Glutathione PeroxidaseAnimalsCell LineEmbryo, MammalianFemaleFetal DeathEmbryonic and Fetal DevelopmentFibroblastsGamma RaysGestational AgeGlutathione PeroxidaseHydrogen PeroxideMice, Inbred C57BLParaquatPregnancy
Funding
- U.S. Department of Veterans Affairs
- National Institutes of Health
- University of Texas Health Science Center at San Antonio
- National Cancer Institute
Citations
809
FWCI
13.26
field-weighted impact
References
26
Percentile
99%
vs. same field & year
Citations per year
Cited by
The Metabolic Underpinnings of Ferroptosis
Cell Metabolism · 2020 · 1,298 citations
Ferroptosis in Cancer Cell Biology
Cancers · 2020 · 336 citations
Selenium, Selenoproteins, and Immunity
Nutrients · 2018 · 858 citations
Trends in oxidative aging theories
Free Radical Biology and Medicine · 2007 · 1,042 citations
The Role of Ferroptosis in Cancer Development and Treatment Response
Frontiers in Pharmacology · 2018 · 460 citations
Radical-free biology of oxidative stress
American Journal of Physiology-Cell Physiology · 2008 · 1,190 citations
Targeting ferroptosis as a vulnerability in cancer
Nature reviews. Cancer · 2022 · 2,045 citations
Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
Cell Metabolism · 2008 · 1,415 citations
References
Tissue-specific functions of individual glutathione peroxidases
Free Radical Biology and Medicine · 1999 · 1,107 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
