Scinovex
articleTop 1% cited

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

Free Radical Biology and Medicine · 2003 · Vol. 34(4) · pp. 496–502
Levi YantQitao RanLin RaoHolly Van RemmenToru ShibataniJason G BelterLucia MottaArlan RichardsonTomas A. Prolla
Selenium in Biological SystemsSex and Gender in HealthcareGPX4Phospholipid-hydroperoxide glutathione peroxidaseLipid peroxidationOxidative stressChemistryAntioxidantCell biologySelenoproteinGlutathione peroxidaseBiochemistry

MeSH terms

Phospholipid Hydroperoxide Glutathione PeroxidaseAnimalsCell LineEmbryo, MammalianFemaleFetal DeathEmbryonic and Fetal DevelopmentFibroblastsGamma RaysGestational AgeGlutathione PeroxidaseHydrogen PeroxideMice, Inbred C57BLParaquatPregnancy

Funding

  • U.S. Department of Veterans Affairs
  • National Institutes of Health
  • University of Texas Health Science Center at San Antonio
  • National Cancer Institute
Citations
809
FWCI
13.26
field-weighted impact
References
26
Percentile
99%
vs. same field & year
Citations per year
Cited by
The Metabolic Underpinnings of Ferroptosis
Cell Metabolism · 2020 · 1,298 citations
Ferroptosis in Cancer Cell Biology
Cancers · 2020 · 336 citations
Selenium, Selenoproteins, and Immunity
Nutrients · 2018 · 858 citations
Trends in oxidative aging theories
Free Radical Biology and Medicine · 2007 · 1,042 citations
The Role of Ferroptosis in Cancer Development and Treatment Response
Frontiers in Pharmacology · 2018 · 460 citations
Radical-free biology of oxidative stress
American Journal of Physiology-Cell Physiology · 2008 · 1,190 citations
Targeting ferroptosis as a vulnerability in cancer
Nature reviews. Cancer · 2022 · 2,045 citations
References
Tissue-specific functions of individual glutathione peroxidases
Free Radical Biology and Medicine · 1999 · 1,107 citations
Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.