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Regulation of translation initiation by FRAP/mTOR

Genes & Development · 2001 · Vol. 15(7) · pp. 807–826
Anne‐Claude GingrasBrian RaughtNahum Sonenberg
Signaling Pathways in DiseaseUbiquitin and proteasome pathwaysRNA and protein synthesis mechanismsBiologyTranslation (biology)Eukaryotic translationPI3K/AKT/mTOR pathwayCell biologyComputational biologyeIF2GeneticsSignal transductionMessenger RNA

MeSH terms

WortmanninPhosphoinositide-3 Kinase InhibitorsAndrostadienesAnimalsAntineoplastic AgentsBinding SitesCarrier ProteinsCell DivisionChromonesDrosophila melanogasterEnergy MetabolismEnzyme InhibitorsEukaryotic CellsFungal ProteinsGene Expression Regulation

Funding

  • Howard Hughes Medical Institute
  • Medical Research Council Canada
  • Canadian Institutes of Health Research
  • Medical Research Council
  • National Cancer Institute
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