articleTop 1% cited
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
Nature Genetics · 1997 · Vol. 16(1) · pp. 64–67
Danny Liaw✉(Columbia University)Deborah J. Marsh(Harvard University)Jing Li(Columbia University)Patricia L. M. Dahia(Harvard University)Steven I. Wang(Columbia University)Zimu Zheng(Harvard University)Shikha Bose(Columbia University)Katherine M. Call(NKT Therapeutics (United States))Hui C. Tsou(Columbia University)Monica Peacoke(Columbia University)Charis Eng(Dana-Farber Cancer Institute)Ramon Parsons(Columbia University)
PI3K/AKT/mTOR signaling in cancerPolyamine Metabolism and ApplicationsMast cells and histamineCowden syndromePTENBiologyBreast cancerGermlineGermline mutationDiseaseCancer researchGeneCancer
MeSH terms
Breast NeoplasmsDNA Mutational AnalysisFemaleHamartoma Syndrome, MultipleHumansMalePedigreePhosphoric Monoester HydrolasesPolymorphism, GeneticGenes, Tumor SuppressorProtein Tyrosine PhosphatasesGerm-Line MutationTumor Suppressor ProteinsPTEN Phosphohydrolase
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References
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
Nature Genetics · 1997 · 2,757 citations
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