article Open AccessTop 1% cited
Two TOR Complexes, Only One of which Is Rapamycin Sensitive, Have Distinct Roles in Cell Growth Control
Molecular Cell · 2002 · Vol. 10(3) · pp. 457–468
Robbie Loewith(University of Basel)Estela Jacinto(University of Basel)Stephan Wullschleger(University of Basel)Anja Lorberg(University of Basel)José L. Crespo(University of Basel)Débora Bonenfant(University of Basel)Wolfgang Oppliger(University of Basel)Paul Jenoe(University of Basel)Michael N. Hall✉(University of Basel)
Fungal and yeast genetics researchFungal Biology and ApplicationsPI3K/AKT/mTOR signaling in cancerBiologyFKBPTOR signalingCell biologySirolimusActin cytoskeletonSaccharomyces cerevisiaeActinCell growthCytoskeleton
MeSH terms
ActinsAnimalsAntifungal AgentsCell LineCytoskeletonFungal ProteinsGlycogenHumansProtein BindingRecombinant Fusion ProteinsSaccharomyces cerevisiaeTissue DistributionSignal TransductionPhosphotransferases (Alcohol Group Acceptor)Genes, Reporter
Citations
1,883
FWCI
15.98
field-weighted impact
References
60
Percentile
100%
vs. same field & year
Citations per year
Cited by
mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
Biochemical Journal · 2008 · 884 citations
The TSC1–TSC2 complex: a molecular switchboard controlling cell growth
Biochemical Journal · 2008 · 1,234 citations
Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks
Biochemical Journal · 2011 · 1,004 citations
Regulation of TORC1 by Rag GTPases in nutrient response
Nature Cell Biology · 2008 · 1,317 citations
Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40
Nature Cell Biology · 2007 · 1,164 citations
mTOR regulation of autophagy
FEBS Letters · 2010 · 2,076 citations
Defining the Role of mTOR in Cancer
Cancer Cell · 2007 · 2,803 citations
Rheb Binds and Regulates the mTOR Kinase
Current Biology · 2005 · 986 citations
References
TOR controls translation initiation and early G1 progression in yeast.
Molecular Biology of the Cell · 1996 · 733 citations
Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels
Analytical Chemistry · 1996 · 9,049 citations
Regulation of translation initiation by FRAP/mTOR
Genes & Development · 2001 · 1,531 citations
Current protocols in molecular biology
Analytical Biochemistry · 1988 · 7,299 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.