reviewTop 1% cited
Nrf2:INrf2 (Keap1) signaling in oxidative stress
Free Radical Biology and Medicine · 2009 · Vol. 47(9) · pp. 1304–1309
James W. Kaspar(University of Maryland, Baltimore)Suryakant Niture(University of Maryland, Baltimore)Anil K. Jaiswal✉(University of Maryland, Baltimore)
Genomics, phytochemicals, and oxidative stressGlutathione Transferases and PolymorphismsAir Quality and Health ImpactsFYNKEAP1Cell biologyPhosphorylationSignal transducing adaptor proteinOxidative stressNuclear export signalChemistrySignal transductionTranscription factor
MeSH terms
Kelch-Like ECH-Associated Protein 1AnimalsHumansSignal TransductionGene Expression Regulation, EnzymologicOxidative StressIntracellular Signaling Peptides and Proteins
Funding
- National Institute of General Medical Sciences
- National Institute of Environmental Health Sciences
Citations
1,632
FWCI
25.68
field-weighted impact
References
104
Percentile
100%
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Citations per year
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References
An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements
Biochemical and Biophysical Research Communications · 1997 · 3,915 citations
Cancer chemoprevention with dietary phytochemicals
Nature reviews. Cancer · 2003 · 2,928 citations
Nrf2 signaling in coordinated activation of antioxidant gene expression
Free Radical Biology and Medicine · 2004 · 1,236 citations
Nrf2 as a novel molecular target for chemoprevention
Cancer Letters · 2004 · 515 citations
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
Molecular and Cellular Biology · 2003 · 1,204 citations
Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2
Carcinogenesis · 2008 · 835 citations
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
Genes & Development · 1999 · 3,543 citations
Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
Biochemical Journal · 2003 · 1,018 citations
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