article Open AccessTop 1% cited
Wnt/β-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis
Developmental Cell · 2005 · Vol. 8(5) · pp. 739–750
Timothy F. Day✉Xizhi Guo(National Institutes of Health)Lisa Garrett‐Beal(National Human Genome Research Institute)Yingzi Yang(National Human Genome Research Institute)
Bone Metabolism and DiseasesWnt/β-catenin signaling in development and cancerConnective tissue disorders researchBiologyWnt signaling pathwayMesenchymal stem cellChondrocyteCell biologyVertebrateProgenitor cellOsteoblastCateninRUNX2
MeSH terms
AnimalsBone DevelopmentCell DifferentiationCytoskeletal ProteinsLac OperonMesodermMice, TransgenicModels, BiologicalOsteoblastsOsteogenesisStem CellsSignal TransductionTrans-ActivatorsIn Situ HybridizationGene Expression Regulation, Developmental
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References
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Developmental Cell · 2002 · 1,599 citations
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
Genes & Development · 1999 · 1,745 citations
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of <i>Sox5</i> and <i>Sox6</i>
Genes & Development · 2002 · 1,713 citations
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