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Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

Cell · 2013 · Vol. 152(5) · pp. 1173–1183
Lei S. QiMatthew H. LarsonLuke A. GilbertJennifer A. DoudnaJonathan S. WeissmanAdam P. ArkinWendell A. Lim
CRISPR and Genetic EngineeringRNA and protein synthesis mechanismsRNA Interference and Gene DeliveryBiologyCRISPRRepurposingGeneComputational biologyGene expressionSequence (biology)GeneticsRNA

MeSH terms

EndodeoxyribonucleasesEscherichia coliStreptococcus pyogenesGene ExpressionRNA InterferenceGene Knockdown TechniquesRNA, Small UntranslatedTranscription Initiation, GeneticTranscription Elongation, Genetic
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References
Efficient genome editing in zebrafish using a CRISPR-Cas system
Nature Biotechnology · 2013 · 2,984 citations
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
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RNA-Guided Human Genome Engineering via Cas9
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RNA-programmed genome editing in human cells
eLife · 2013 · 2,139 citations
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Nature Methods · 2008 · 14,174 citations
Evolution and classification of the CRISPR–Cas systems
Nature Reviews Microbiology · 2011 · 2,472 citations
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Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression · Scinovex