review Open Access
p53: puzzle and paradigm.
Genes & Development · 1996 · Vol. 10(9) · pp. 1054–1072
L J Ko✉(Columbia University)Carol Prives(Columbia University)
Cancer-related Molecular PathwaysCancer Research and TreatmentsMicrotubule and mitosis dynamicsBiologyComputational biologyEvolutionary biologyGenetics
MeSH terms
AnimalsBase SequenceCell DifferentiationHumansMolecular Sequence DataNeoplasmsTranscription, GeneticSignal TransductionGenes, p53Tumor Suppressor Protein p53Apoptosis
Funding
- National Institutes of Health
Citations
2,349
FWCI
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field-weighted impact
References
249
Percentile
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vs. same field & year
Citations per year
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References
mdm2 expression is induced by wild type p53 activity.
The EMBO Journal · 1993 · 1,285 citations
Inhibition of cyclin-dependent kinases by p21.
Molecular Biology of the Cell · 1995 · 1,018 citations
WAF1, a potential mediator of p53 tumor suppression
Cell · 1993 · 8,369 citations
Tumor spectrum analysis in p53-mutant mice
Current Biology · 1994 · 2,066 citations
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
Cell · 1993 · 5,653 citations
The p53-mdm-2 autoregulatory feedback loop.
Genes & Development · 1993 · 1,791 citations
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