reviewTop 1% cited
Regulation of p53 in response to DNA damage
Oncogene · 1999 · Vol. 18(53) · pp. 7644–7655
Nicholas D. Lakin✉(Wellcome Trust)Stephen P. Jackson(University of Cambridge)
Cancer-related Molecular PathwaysEpigenetics and DNA MethylationCancer Research and TreatmentsDNA damageBiologyDNADNA repairPhosphorylationCell biologyAcetylationTranscription factorGeneBiochemistry
MeSH terms
Adenosine TriphosphatasesAnimalsDNA DamageDNA HelicasesDNA-Binding ProteinsHumansNuclear ProteinsProtein Processing, Post-TranslationalProto-Oncogene ProteinsSignal TransductionTrans-ActivatorsTumor Suppressor Protein p53Protein Serine-Threonine KinasesCell Cycle ProteinsTumor Suppressor Proteins
Citations
995
FWCI
17.82
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References
129
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References
mdm2 expression is induced by wild type p53 activity.
The EMBO Journal · 1993 · 1,285 citations
p53, the Cellular Gatekeeper for Growth and Division
Cell · 1997 · 7,678 citations
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
FEBS Letters · 1997 · 1,932 citations
p53: puzzle and paradigm.
Genes & Development · 1996 · 2,349 citations
The p53-mdm-2 autoregulatory feedback loop.
Genes & Development · 1993 · 1,791 citations
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