review Open AccessTop 1% cited
Many cuts to ruin: a comprehensive update of caspase substrates
Cell Death and Differentiation · 2003 · Vol. 10(1) · pp. 76–100
Utz Fischer✉(Heinrich Heine University Düsseldorf)Reiner U. Jänicke(Heinrich Heine University Düsseldorf)Klaus Schulze‐Osthoff(Hochschule Düsseldorf University of Applied Sciences)
Cell death mechanisms and regulationUbiquitin and proteasome pathwaysAutophagy in Disease and TherapyCaspaseCleavage (geology)Cell biologyCaspase 2Programmed cell deathApoptosisBiologyCell fate determinationNLRP1Cell
MeSH terms
AnimalsBinding SitesEukaryotic CellsHumansProteinsSignal TransductionApoptosisCaspases
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References
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
Annual Review of Biochemistry · 1999 · 2,764 citations
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Cell · 1998 · 4,423 citations
Activation and Caspase-mediated Inhibition of PARP: A Molecular Switch between Fibroblast Necrosis and Apoptosis in Death Receptor Signaling
Molecular Biology of the Cell · 2002 · 495 citations
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
Nature Cell Biology · 2001 · 1,271 citations
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