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EXTENT OF RESECTION AND SURVIVAL IN GLIOBLASTOMA MULTIFORME

Neurosurgery · 2008 · Vol. 62(3) · pp. 564–576

Walter Stummer✉(Goethe University Frankfurt)H. J. Reulen(Goethe University Frankfurt)Thomas R. Meinel(Goethe University Frankfurt)Uwe Pichlmeier(Goethe University Frankfurt)Wiebke Schumacher(Goethe University Frankfurt)Jörg‐Christian Tonn(Goethe University Frankfurt)Veit Rohde(Goethe University Frankfurt)Falk Oppel(Goethe University Frankfurt)Bernd Turowski(Goethe University Frankfurt)Christian Woiciechowsky(Goethe University Frankfurt)Kea Franz(Goethe University Frankfurt)Torsten Pietsch(Goethe University Frankfurt)

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Abstract

Treatment bias was demonstrated regarding resection and second-line therapies. However, bias and imbalances were controllable in the cohorts available from the 5-aminolevulinic acid study so that the present data now provide Level 2b evidence (Oxford Centre for Evidence-based Medicine) that survival depends on complete resection of enhancing tumor in glioblastoma multiforme.

Glioma Diagnosis and Treatment Brain Metastases and Treatment Meningioma and schwannoma managementMedicineGlioblastomaMagnetic resonance imagingSurgeryBrain tumorKarnofsky Performance StatusMultivariate analysisRadiologyInternal medicineChemotherapy

MeSH terms

AdolescentAdultAgedBrain NeoplasmsFemaleGermanyGlioblastomaHumansMaleMiddle AgedNeoplasm Recurrence, LocalRisk FactorsSensitivity and SpecificityReproducibility of ResultsBias

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