articleTop 10% cited
Fluorescence-guided resection of glioblastoma multiforme utilizing 5-ALA-induced porphyrins: a prospective study in 52 consecutive patients
Journal of neurosurgery · 2000 · Vol. 93(6) · pp. 1003–1013
Walter Stummer✉(Ludwig-Maximilians-Universität München)Alexander NovotnyHerbert SteppClaudia GoetzK. BiseHans J. Reulen
Abstract
The observations in this study indicate the usefulness of 5-ALA-induced tumor fluorescence for guiding tumor resection. The completeness of resection, as determined intraoperatively from residual tissue fluorescence, was related to postoperative MR imaging findings and to survival in patients suffering from GBM.
Glioma Diagnosis and TreatmentNanoplatforms for cancer theranosticsOcular Oncology and TreatmentsMedicineMagnetic resonance imagingGlioblastomaPerioperativeUnivariate analysisProspective cohort studyRadiologyResectionSurgeryMultivariate analysis
MeSH terms
AdultAgedAminolevulinic AcidBrainBrain NeoplasmsFemaleFluorescenceGlioblastomaHumansMaleMiddle AgedPorphyrinsProspective StudiesSurvival Rate
Citations
871
FWCI
7.64
field-weighted impact
References
44
Percentile
98%
vs. same field & year
Citations per year
Cited by
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial
The Lancet Oncology · 2006 · 3,314 citations
Photodynamic therapy for cancer
Nature reviews. Cancer · 2003 · 6,614 citations
EXTENT OF RESECTION AND SURVIVAL IN GLIOBLASTOMA MULTIFORME
Neurosurgery · 2008 · 1,016 citations
Photodynamic therapy of cancer: An update
CA A Cancer Journal for Clinicians · 2011 · 5,066 citations
References
Effect of the Extent of Surgical Resection on Survival and Quality of Life in Patients with Supratentorial Glioblastomas and Anaplastic Astrocytomas
Neurosurgery · 1987 · 470 citations
Intraoperative Detection of Malignant Gliomas by 5-Aminolevulinic Acid-induced Porphyrin Fluorescence
Neurosurgery · 1998 · 679 citations
Imaging-based stereotaxic serial biopsies in untreated intracranial glial neoplasms
Journal of neurosurgery · 1987 · 816 citations
Nonparametric Estimation from Incomplete Observations
Journal of the American Statistical Association · 1958 · 38,793 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.