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An extent of resection threshold for newly diagnosed glioblastomas

Journal of neurosurgery · 2011 · Vol. 115(1) · pp. 3–8

Nader Sanai✉Mei‐Yin C. Polley(University of California, San Francisco)Michael W. McDermott(University of California, San Francisco)Andrew T. Parsa(University of California, San Francisco)Mitchel S. Berger(University of California, San Francisco)

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Abstract

For patients with newly diagnosed GBMs, aggressive EOR equates to improvement in overall survival, even at the highest levels of resection. Interestingly, subtotal resections as low as 78% also correspond to a survival benefit.

Glioma Diagnosis and Treatment Meningioma and schwannoma management Brain Metastases and TreatmentMedicineGlioblastomaSurvival analysisProportional hazards modelSurgeryRecursive partitioningOncologyInternal medicine

MeSH terms

AdultAgedAged, 80 and overAntineoplastic AgentsBrain NeoplasmsCombined Modality TherapyFemaleFollow-Up StudiesGlioblastomaHumansMagnetic Resonance ImagingMaleMiddle AgedPrognosisSurvival Rate

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The influence of maximum safe resection of glioblastoma on survival in 1229 patients: Can we do better than gross-total resection?