articleTop 1% cited
Construction of Nitrogen‐Containing Heterocycles by CH Bond Functionalization
Chemistry - A European Journal · 2009 · Vol. 15(24) · pp. 5874–5883
Praew Thansandote✉(University of Toronto)Mark Lautens(University of Toronto)
Abstract
Nitrogen heterocycles are abundant in natural products and pharmaceuticals. An emerging interest among synthetic chemists is to use C-H functionalization to construct the nitrogen-containing core of these heterocycles. The following article will provide a brief overview of this concept with respect to the type of C-H bond functionalized.
Catalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsCyclopropane Reaction MechanismsSurface modificationNitrogenChemistryCombinatorial chemistryOrganic chemistry
MeSH terms
Heterocyclic CompoundsHydrogen BondingNitrogenMolecular Structure
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References
Synthesis of 2,3-Disubstituted Indoles via Palladium-Catalyzed Annulation of Internal Alkynes
The Journal of Organic Chemistry · 1998 · 597 citations
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