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Construction of Nitrogen‐Containing Heterocycles by CH Bond Functionalization

Chemistry - A European Journal · 2009 · Vol. 15(24) · pp. 5874–5883
Praew ThansandoteMark Lautens

Abstract

Nitrogen heterocycles are abundant in natural products and pharmaceuticals. An emerging interest among synthetic chemists is to use C-H functionalization to construct the nitrogen-containing core of these heterocycles. The following article will provide a brief overview of this concept with respect to the type of C-H bond functionalized.

Catalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsCyclopropane Reaction MechanismsSurface modificationNitrogenChemistryCombinatorial chemistryOrganic chemistry

MeSH terms

Heterocyclic CompoundsHydrogen BondingNitrogenMolecular Structure
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